BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells

Autophagy is the basic catabolic mechanism that involves cell degradation of unnecessary or dysfunctional cellular components. Autophagy has a controversial role in cancer – both in protecting against tumor progression by isolation of damaged organelles, or by potentially contributing to cancer grow...

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Vydáno v:Oncotarget
Hlavní autoři: Goulielmaki, Maria, Koustas, Evangelos, Moysidou, Eirini, Vlassi, Margarita, Sasazuki, Takehiko, Shirasawa, Senji, Zografos, George, Oikonomou, Eftychia, Pintzas, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891035/
https://ncbi.nlm.nih.gov/pubmed/26802026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6942
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