Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

Rho family GTPases are activated with precise spatiotemporal control by guanine nucleotide exchange factors (GEFs). Guanine exchange factor H1 (GEF-H1), a RhoA activator, is thought to act as an integrator of microtubule (MT) and actin dynamics in diverse cell functions. Here we identify a GEF-H1 au...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Azoitei, Mihai L., Noh, Jungsik, Marston, Daniel J., Roudot, Philippe, Marshall, Christopher B., Daugird, Timothy A., Lisanza, Sidney L., Sandí, María-José, Ikura, Mitsu, Sondek, John, Rottapel, Robert, Hahn, Klaus M., Danuser, Gaudenz
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719461/
https://ncbi.nlm.nih.gov/pubmed/31420453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812073
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