Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress

Por Xu, Lin, Holscher, Christian, Anwyl, Roger, Rowan, Michael J.
Publicado em 1998

NMDA receptor- and metabotropic glutamate receptor-dependent synaptic plasticity induced by high frequency stimulation in the rat dentate gyrus in vitro

Por Wu, Jinquian, Rush, Anthony, Rowan, Michael J, Anwyl, Roger
Publicado em 2001

Synaptic plasticity in animal models of early Alzheimer's disease.

Por Rowan, Michael J, Klyubin, Igor, Cullen, William K, Anwyl, Roger
Publicado em 2003

GluN2B subunit-containing NMDA receptor antagonists prevent Aβ-mediated synaptic plasticity disruption in vivo

Por Hu, Neng-Wei, Klyubin, Igor, Anwyl, Roger, Rowan, Michael J.
Publicado em 2009

Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory

Por Klyubin, Igor, Cullen, William K, Hu, Neng-Wei, Rowan, Michael J
Publicado em 2012

Inherent Anti-amyloidogenic Activity of Human Immunoglobulin γ Heavy Chains

Por Adekar, Sharad P., Klyubin, Igor, Macy, Sally, Rowan, Michael J., Solomon, Alan, Dessain, Scott K., O'Nuallain, Brian
Publicado em 2010

Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo

Por Klyubin, Igor, Ondrejcak, Tomas, Hayes, Jennifer, Cullen, William K., Mably, Alexandra J., Walsh, Dominic M., Rowan, Michael J.
Publicado em 2014

Autophosphorylation of αCaMKII is not a general requirement for NMDA receptor-dependent LTP in the adult mouse

Por Cooke, Sam F, Wu, Jianqun, Plattner, Florian, Errington, Michael, Rowan, Michael, Peters, Marco, Hirano, Ayumi, Bradshaw, Karl D, Anwyl, Roger, Bliss, Timothy V P, Giese, K Peter
Publicado em 2006

mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo

Por Hu, Neng-Wei, Nicoll, Andrew J., Zhang, Dainan, Mably, Alexandra J., O’Malley, Tiernan, Purro, Silvia A., Terry, Cassandra, Collinge, John, Walsh, Dominic M., Rowan, Michael J.
Publicado no Nat Commun (2014)

Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms

Por Harte, Níal P., Klyubin, Igor, McCarthy, Eoin K., Min, Soyoung, Garrahy, Sarah Ann, Xie, Yongjing, Davey, Gavin P., Boland, John J., Rowan, Michael J., Mok, K. Hun
Publicado no J Biol Chem (2015)

Secreted Amyloid β-Proteins in a Cell Culture Model Include N-Terminally Extended Peptides That Impair Synaptic Plasticity

Por Welzel, Alfred T., Maggio, John E., Shankar, Ganesh M., Walker, Donald E., Ostaszewski, Beth L., Li, Shaomin, Klyubin, Igor, Rowan, Michael J., Seubert, Peter, Walsh, Dominic M., Selkoe, Dennis J.
Publicado em 2014

Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity

Por Klyubin, Igor, Nicoll, Andrew J., Khalili-Shirazi, Azadeh, Farmer, Michael, Canning, Stephanie, Mably, Alexandra, Linehan, Jacqueline, Brown, Alexander, Wakeling, Madeleine, Brandner, Sebastian, Walsh, Dominic M., Rowan, Michael J., Collinge, John
Publicado em 2014

A Monoclonal Antibody Against Synthetic Aβ Dimer Assemblies Neutralizes Brain-Derived Synaptic Plasticity-Disrupting Aβ

Por O'Nuallain, Brian, Klyubin, Igor, Mc Donald, Jessica M., Foster, James S., Welzel, Alfred, Barry, Andrew, Dykoski, Richard K., Cleary, James P., Gebbink, Martijn F.B.G., Rowan, Michael J., Walsh, Dominic M.
Publicado em 2011

Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization

Por Klyubin, Igor, Betts, Vicki, Welzel, Alfred T., Blennow, Kaj, Zetterberg, Henrik, Wallin, Anders, Lemere, Cynthia A., Cullen, William K., Peng, Ying, Wisniewski, Thomas, Selkoe, Dennis J., Anwyl, Roger, Walsh, Dominic M., Rowan, Michael J.
Publicado em 2008

Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human Aß-induced synaptic dysfunction in individual freely behaving pre-plaque transg...

Por Qi, Yingjie, Klyubin, Igor, Harney, Sarah C, Hu, NengWei, Cullen, William K, Grant, Marianne K, Steffen, Julia, Wilson, Edward N, Do Carmo, Sonia, Remy, Stefan, Fuhrmann, Martin, Ashe, Karen H, Cuello, A Claudio, Rowan, Michael J
Publicado no Acta Neuropathol Commun (2014)

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

Por Freir, Darragh B., Nicoll, Andrew J., Klyubin, Igor, Panico, Silvia, Mc Donald, Jessica M., Risse, Emmanuel, Asante, Emmanuel A., Farrow, Mark A., Sessions, Richard B., Saibil, Helen R., Clarke, Anthony R., Rowan, Michael J., Walsh, Dominic M., Collinge, John
Publicado em 2011

Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo

Por An, Kyongman, Klyubin, Igor, Kim, Youngkyu, Jung, Jung Hoon, Mably, Alexandra J, O’Dowd, Sean T, Lynch, Timothy, Kanmert, Daniel, Lemere, Cynthia A, Finan, Gina M, Park, Joon Won, Kim, Tae-Wan, Walsh, Dominic M, Rowan, Michael J, Kim, Joung-Hun
Publicado no Mol Brain (2013)

Amyloid β-Protein Dimers Isolated Directly from Alzheimer Brains Impair Synaptic Plasticity and Memory

Por Shankar, Ganesh M., Li, Shaomin, Mehta, Tapan H., Garcia-Munoz, Amaya, Shepardson, Nina E., Smith, Imelda, Brett, Francesca M., Farrell, Michael A., Rowan, Michael J., Lemere, Cynthia A., Regan, Ciaran M., Walsh, Dominic M., Sabatini, Bernardo L., Selkoe, Dennis J.
Publicado em 2008

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

Por Kotilinek, Linda A., Westerman, Marcus A., Wang, Qinwen, Panizzon, Kimberly, Lim, Giselle P., Simonyi, Agnes, Lesne, Sylvain, Falinska, Agnieszka, Younkin, Linda H., Younkin, Steven G., Rowan, Michael, Cleary, James, Wallis, Roi Ann, Sun, GraceY., Cole, Greg, Frautschy, Sally, Anwyl, Roger, Ashe, Karen H.
Publicado em 2008

A Human Monoclonal IgG That Binds Aβ Assemblies and Diverse Amyloids Exhibits Anti-Amyloid Activities In Vitro and In Vivo

Por Levites, Yona, O'Nuallain, Brian, Puligedda, Rama Devudu, Ondrejcak, Tomas, Adekar, Sharad P., Chen, Cindy, Cruz, Pedro E., Rosario, Awilda M., Macy, Sallie, Mably, Alexandra J., Walsh, Dominic M., Vidal, Ruben, Solomon, Alan, Brown, Daniel, Rowan, Michael J., Golde, Todd E., Dessain, Scott K.
Publicado no J Neurosci (2015)