New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases

Por Hölscher, Christian
Publicado no Neural Regen Res (2014)

Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

Por Hunter Kerry, Hölscher Christian
Publicado em 2012-03-01

Perirhinal Cortex Neuronal Activity is Actively Related to Working Memory in the Macaque

Por Hölscher, Christian, Rolls, Edmund T.
Publicado em 2002

Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

Por Hunter, Kerry, Hölscher, Christian
Publicado em 2012

Chronic Treatment with the GLP1 Analogue Liraglutide Increases Cell Proliferation and Differentiation into Neurons in an AD Mouse Model

Por Parthsarathy, Vadivel, Hölscher, Christian
Publicado em 2013

Neuroprotective effects of D-Ala(2)GIP on Alzheimer's disease biomarkers in an APP/PS1 mouse model

Por Faivre, Emilie, Hölscher, Christian
Publicado em 2013

Synaptic Plasticity in the Hippocampus of a APP/PS1 Mouse Model of Alzheimer's Disease Is Impaired in Old but Not Young Mice

Por Gengler, Simon, Hamilton, Alison, Hölscher, Christian
Publicado em 2010

Liraglutide restores chronic ER stress, autophagy impairments and apoptotic signalling in SH-SY5Y cells

Por Panagaki, Theodora, Michael, Maria, Hölscher, Christian
Publicado no Sci Rep (2017)

Anaesthesia generates neuronal insulin resistance by inducing hypothermia

Por Holscher, Christian, van Aalten, Lidy, Sutherland, Calum
Publicado em 2008

Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress

Por Xu, Lin, Holscher, Christian, Anwyl, Roger, Rowan, Michael J.
Publicado em 1998

Are Alzheimer’s disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones?

Por Hölscher, Christian, De Felice, Fernanda G., Greig, Nigel H., Ferreira, Sergio T.
Publicado no Neuropharmacology (2018)

Wide-ranging alterations in the brain fatty acid complement of subjects with late Alzheimer’s disease as detected by GC-MS

Por Nasaruddin, Muhammad Luqman, Hölscher, Christian, Kehoe, Patrick, Graham, Stewart Francis, Green, Brian Desmond
Publicado no Am J Transl Res (2016)

Neuroprotective role of (Val(8))GLP-1-Glu-PAL in an in vitro model of Parkinson's disease

Por Li, Lin, Liu, Ke, Zhao, Juan, Holscher, Christian, Li, Guang-lai, Liu, Yue-ze
Publicado no Neural Regen Res (2016)

Defects in Peroxisomal 6-Phosphogluconate Dehydrogenase Isoform PGD2 Prevent Gametophytic Interaction in Arabidopsis thaliana

Por Hölscher, Christian, Lutterbey, Marie-Christin, Lansing, Hannes, Meyer, Tanja, Fischer, Kerstin, von Schaewen, Antje
Publicado no Plant Physiol (2016)

Neural Circuit Interactions between the Dorsal Raphe Nucleus and the Lateral Hypothalamus: An Experimental and Computational Study

Por Jalewa, Jaishree, Joshi, Alok, McGinnity, T. Martin, Prasad, Girijesh, Wong-Lin, KongFatt, Hölscher, Christian
Publicado em 2014

Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer’s Disease (AD) Pathology Than in Severe AD Pathology

Por Nasaruddin, Muhammad L., Pan, Xiaobei, McGuinness, Bernadette, Passmore, Peter, Kehoe, Patrick G., Hölscher, Christian, Graham, Stewart F., Green, Brian D.
Publicado no Metabolites (2018)

Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

Por Olmos-Alonso, Adrian, Schetters, Sjoerd T. T., Sri, Sarmi, Askew, Katharine, Mancuso, Renzo, Vargas-Caballero, Mariana, Holscher, Christian, Perry, V. Hugh, Gomez-Nicola, Diego
Publicado no Brain (2016)

Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence

Por Freiherr, Jessica, Hallschmid, Manfred, Frey, William H., Brünner, Yvonne F., Chapman, Colin D., Hölscher, Christian, Craft, Suzanne, De Felice, Fernanda G., Benedict, Christian
Publicado em 2013

Integrating microRNA and messenger RNA expression profiles in a rat model of deep vein thrombosis

Por Jin, Qian-Qian, Sun, Jun-Hong, Du, Qiu-Xiang, Lu, Xiao-Jun, Zhu, Xi-Yan, Fan, Hao-Liang, Hölscher, Christian, Wang, Ying-Yuan
Publicado no Int J Mol Med (2017)

A Novel Retro-Inverso Peptide Inhibitor Reduces Amyloid Deposition, Oxidation and Inflammation and Stimulates Neurogenesis in the APPswe/PS1ΔE9 Mouse Model of Alzheimer’s Disease...

Por Parthsarathy, Vadivel, McClean, Paula L., Hölscher, Christian, Taylor, Mark, Tinker, Claire, Jones, Glynn, Kolosov, Oleg, Salvati, Elisa, Gregori, Maria, Masserini, Massimo, Allsop, David
Publicado em 2013