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Intranasal Insulin as a Treatment for Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence

Research in animals and humans has associated Alzheimer’s disease (AD) with decreased cerebrospinal fluid levels of insulin in combination with decreased insulin sensitivity (insulin resistance) in the brain. This phenomenon is accompanied by attenuated receptor expression of insulin and insulin-lik...

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Détails bibliographiques
Auteurs principaux: Freiherr, Jessica, Hallschmid, Manfred, Frey, William H., Brünner, Yvonne F., Chapman, Colin D., Hölscher, Christian, Craft, Suzanne, De Felice, Fernanda G., Benedict, Christian
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709085/
https://ncbi.nlm.nih.gov/pubmed/23719722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-013-0076-8
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