Direct Control of Cell Cycle Gene Expression by Proto-Oncogene Product ACTR, and Its Autoregulation Underlies Its Transforming Activity

Por Louie, Maggie C., Revenko, Alexey S., Zou, June X., Yao, Jennifer, Chen, Hong-Wu
Publicado em 2006

ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERα, is required for coregulator occupancy and chromatin modification

Por Zou, June X., Revenko, Alexey S., Li, Li B., Gemo, Abigael T., Chen, Hong-Wu
Publicado em 2007

Chromatin Loading of E2F-MLL Complex by Cancer-Associated Coregulator ANCCA via Reading a Specific Histone Mark

Por Revenko, Alexey S., Kalashnikova, Ekaterina V., Gemo, Abigael T., Zou, June X., Chen, Hong-Wu
Publicado em 2010

Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes

Por Tanowitz, Michael, Hettrick, Lisa, Revenko, Alexey, Kinberger, Garth A., Prakash, Thazha P., Seth, Punit P.
Publicado no Nucleic Acids Res (2017)

Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice

Por Chen, Zu-Lin, Revenko, Alexey S., Singh, Pradeep, MacLeod, A. Robert, Norris, Erin H., Strickland, Sidney
Publicado no Blood (2017)

Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides

Por Wang, Shiyu, Allen, Nickolas, Vickers, Timothy A, Revenko, Alexey S, Sun, Hong, Liang, Xue-hai, Crooke, Stanley T
Publicado no Nucleic Acids Res (2018)

Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer’s disease

Por Baker, Sarah K., Chen, Zu-Lin, Norris, Erin H., Revenko, Alexey S., MacLeod, A. Robert, Strickland, Sidney
Publicado no Proc Natl Acad Sci U S A (2018)

Knockdown of circulating C1 inhibitor induces neurovascular impairment, glial cell activation, neuroinflammation, and behavioral deficits

Por Farfara, Dorit, Feierman, Emily, Richards, Allison, Revenko, Alexey S., MacLeod, Robert A., Norris, Erin H., Strickland, Sidney
Publicado no Glia (2019)

Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding

Por Revenko, Alexey S., Gao, Dacao, Crosby, Jeff R., Bhattacharjee, Gourab, Zhao, Chenguang, May, Chris, Gailani, David, Monia, Brett P., MacLeod, A. Robert
Publicado no Blood (2011)

Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines

Por Linnane, Emily, Davey, Paul, Zhang, Pei, Puri, Sanyogitta, Edbrooke, Mark, Chiarparin, Elisabetta, Revenko, Alexey S, Macleod, A Robert, Norman, Jim C, Ross, Sarah J
Publicado no Nucleic Acids Res (2019)

Limited role of kininogen in the host response during gram-negative pneumonia-derived sepsis

Por Ding, Chao, van ’t Veer, Cornelis, Roelofs, Joris J. T. H., Shukla, Meenal, McCrae, Keith R., Revenko, Alexey S., Crosby, Jeff, van der Poll, Tom
Publicado no Am J Physiol Lung Cell Mol Physiol (2018)

The contact system proteases play disparate roles in streptococcal sepsis

Por Köhler, Juliane, Maletzki, Claudia, Koczan, Dirk, Frank, Marcus, Trepesch, Carolin, Revenko, Alexey S., Crosby, Jeffrey R., Macleod, A. Robert, Mikkat, Stefan, Oehmcke-Hecht, Sonja
Publicado no Haematologica (2020)

ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and E...

Por Kalashnikova, Ekaterina V., Revenko, Alexey S., Gemo, Abigael T., Andrews, Nicolas P., Tepper, Clifford G., Zou, June X., Cardiff, Robert D., Borowsky, Alexander D., Chen, Hong-Wu
Publicado em 2010

Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis

Por Köhler, Juliane, Maletzki, Claudia, Koczan, Dirk, Frank, Marcus, Springer, Armin, Steffen, Carolin, Revenko, Alexey S., MacLeod, A.Robert, Mikkat, Stefan, Kreikemeyer, Bernd, Oehmcke-Hecht, Sonja
Publicado no EBioMedicine (2020)

Colon Cancer Growth and Dissemination Relies upon Thrombin, Stromal PAR-1, and Fibrinogen

Por Adams, Gregory N., Rosenfeldt, Leah, Frederick, Malinda, Miller, Whitney, Waltz, Dusty, Kombrinck, Keith, McElhinney, Kathryn E., Flick, Matthew J., Monia, Brett P., Revenko, Alexey S., Palumbo, Joseph S.
Publicado no Cancer Res (2015)

Antithrombotic Effect of Antisense Factor XI Oligonucleotide Treatment in Primates

Por Crosby, Jeffrey R., Marzec, Ulla, Revenko, Alexey S., Zhao, Chenguang, Gao, Dacao, Matafonov, Anton, Gailani, David, MacLeod, A. Robert, Tucker, Erik I., Gruber, Andras, Hanson, Stephen R., Monia, Brett P.
Publicado em 2013

Thrombin drives tumorigenesis in colitis-associated colon cancer

Por Turpin, Brian, Miller, Whitney, Rosenfeldt, Leah, Kombrinck, Keith, Flick, Matthew J., Steinbrecher, Kris A., Harmel-Laws, Eleana, Mullins, Eric S., Shaw, Maureen, Witte, David P., Revenko, Alexey, Monia, Brett, Palumbo, Joseph S.
Publicado no Cancer Res (2014)

Kininogen deficiency or depletion reduces enhanced pause independent of pulmonary inflammation in a house dust mite-induced murine asthma model

Por Yang, Jack, van ’t Veer, Cornelis, Roelofs, Joris J. T. H., van Heijst, Jeroen W. J., de Vos, Alex F., McCrae, Keith R., Revenko, Alexey S., Crosby, Jeff, van der Poll, Tom
Publicado no Am J Physiol Lung Cell Mol Physiol (2019)

The non-coding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells

Por Gutschner, Tony, Hämmerle, Monika, Eißmann, Moritz, Hsu, Jeff, Kim, Youngsoo, Hung, Gene, Revenko, Alexey, Arun, Gayatri, Stentrup, Marion, Groß, Matthias, Zörnig, Martin, MacLeod, A. Robert, Spector, David L., Diederichs, Sven
Publicado em 2012

Hepatic thrombopoietin gene silencing reduces platelet count and breast cancer progression in transgenic MMTV-PyMT mice

Por Shirai, Toshiaki, Revenko, Alexey S., Tibbits, Justin, Ngo, Anh T. P., Mitrugno, Annachiara, Healy, Laura D., Johnson, Jennifer, Tucker, Erik I., Hinds, Monica T., Coussens, Lisa M., McCarty, Owen J. T., Monia, Brett P., Gruber, András
Publicado no Blood Adv (2019)