Glycogen Synthase Kinase 3β Functions To Specify Gene-Specific, NF-κB-Dependent Transcription

Por Steinbrecher, Kris A., Wilson, Willie, Cogswell, Patricia C., Baldwin, Albert S.
Publicado em 2005

Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen

Por Mann, Elizabeth A, Harmel-Laws, Eleana, Cohen, Mitchell B, Steinbrecher, Kris A
Publicado em 2013

Guanylate Cyclase C Deficiency Causes Severe Inflammation in a Murine Model of Spontaneous Colitis

Por Harmel-Laws, Eleana, Mann, Elizabeth A., Cohen, Mitchell B., Steinbrecher, Kris A.
Publicado em 2013

Targeted Inactivation of the Mouse Guanylin Gene Results in Altered Dynamics of Colonic Epithelial Proliferation

Por Steinbrecher, Kris A., Wowk, Steve A., Rudolph, Jeffrey A., Witte, David P., Cohen, Mitchell B.
Publicado em 2002

Loss of Guanylyl Cyclase C (GCC) Signaling Leads to Dysfunctional Intestinal Barrier

Por Han, Xiaonan, Mann, Elizabeth, Gilbert, Shila, Guan, Yanfang, Steinbrecher, Kris A., Montrose, Marshall H., Cohen, Mitchell B.
Publicado em 2011

Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice

Por Waddell, Amanda, Ahrens, Richard, Tsai, Yi Ting, Sherrill, Joseph D., Denson, Lee A., Steinbrecher, Kris A., Hogan, Simon P.
Publicado em 2013

Activation of TGF‐β activated kinase 1 promotes colon mucosal pathogenesis in inflammatory bowel disease

Por Liu, Zhiwei, Kong, Fansheng, Vallance, Jefferson E., Harmel‐Laws, Eleana, Amarachintha, Surya, Steinbrecher, Kris A., Rosen, Michael J., Bhattacharyya, Sandip
Publicado no Physiol Rep (2017)

Commensal microbes drive intestinal inflammation by IL-17–producing CD4(+) T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2

Por Xin, Lijun, Jiang, Tony T., Chaturvedi, Vandana, Kinder, Jeremy M., Ertelt, James M., Rowe, Jared H., Steinbrecher, Kris A., Way, Sing Sing
Publicado em 2014

Myeloid-derived NF-κB negative regulation of PU.1 and cEBPβ-driven pro-inflammatory cytokine production restrains LPS-induced Shock

Por Vanoni, Simone, Tsai, Yi Ting, Waddell, Amanda, Waggoner, Lisa, Klarquist, Jared, Divanovic, Senad, Hoebe, Kasper, Steinbrecher, Kris A., Hogan, Simon P.
Publicado no Innate Immun (2016)

Murine Guanylate Cyclase C Regulates Colonic Injury and Inflammation

Por Steinbrecher, Kris A., Harmel-Laws, Eleana, Garin-Laflam, Monica P., Mann, Elizabeth A., Bezerra, Lucas D., Hogan, Simon P., Cohen, Mitchell B.
Publicado em 2011

Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage

Por Ikpa, Pauline T., Sleddens, Hein F. B. M., Steinbrecher, Kris A., Peppelenbosch, Maikel P., de Jonge, Hugo R., Smits, Ron, Bijvelds, Marcel J. C.
Publicado no Histochem Cell Biol (2016)

Deletion of Fanca or Fancd2 dysregulates Treg in mice

Por Du, Wei, Erden, Ozlem, Wilson, Andrew, Sipple, Jared M., Schick, Jonathan, Mehta, Parinda, Myers, Kasiani C., Steinbrecher, Kris A., Davies, Stella M., Pang, Qishen
Publicado em 2014

Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis

Por Begg, Denovan P., Steinbrecher, Kris A., Mul, Joram D., Chambers, Adam P., Kohli, Rohit, Haller, April, Cohen, Mitchell B., Woods, Stephen C., Seeley, Randy J.
Publicado em 2014

Thrombin drives tumorigenesis in colitis-associated colon cancer

Por Turpin, Brian, Miller, Whitney, Rosenfeldt, Leah, Kombrinck, Keith, Flick, Matthew J., Steinbrecher, Kris A., Harmel-Laws, Eleana, Mullins, Eric S., Shaw, Maureen, Witte, David P., Revenko, Alexey, Monia, Brett, Palumbo, Joseph S.
Publicado no Cancer Res (2014)

Interleukin-13 (IL-13)/IL-13 Receptor α1 (IL-13Rα1) Signaling Regulates Intestinal Epithelial Cystic Fibrosis Transmembrane Conductance Regulator Channel-dependent Cl(−) Secretion...

Por Wu, David, Ahrens, Richard, Osterfeld, Heather, Noah, Taeko K., Groschwitz, Katherine, Foster, Paul S., Steinbrecher, Kris A., Rothenberg, Marc E., Shroyer, Noah F., Matthaei, Klaus I., Finkelman, Fred D., Hogan, Simon P.
Publicado em 2011

Immunosuppressive CD71(+) erythroid cells compromise neonatal host defence against infection

Por Elahi, Shokrollah, Ertelt, James M., Kinder, Jeremy M., Jiang, Tony T., Zhang, Xuzhe, Xin, Lijun, Chaturvedi, Vandana, Strong, Beverly S., Qualls, Joseph E., Steinbrecher, Kris A., Kalfa, Theodosia A., Shaaban, Aimen F., Way, Sing Sing
Publicado em 2013

IL-17 Signaling Accelerates the Progression of Nonalcoholic Fatty Liver Disease in Mice

Por Harley, Isaac TW, Stankiewicz, Traci E, Giles, Daniel A, Softic, Samir, Flick, Leah M, Cappelletti, Monica, Sheridan, Rachel, Xanthakos, Stavra A, Steinbrecher, Kris A, Sartor, R Balfour, Kohli, Rohit, Karp, Christopher L, Divanovic, Senad
Publicado em 2014

Thermoneutral housing exacerbates non-alcoholic fatty liver disease in mice and allows for sex-independent disease modeling

Por Giles, Daniel A, Moreno-Fernandez, Maria E, Stankiewicz, Traci E, Graspeuntner, Simon, Cappelletti, Monica, Wu, David, Mukherjee, Rajib, Chan, Calvin C, Lawson, Matthew J, Klarquist, Jared, Sünderhauf, Annika, Softic, Samir, Kahn, C Ronald, Stemmer, Kerstin, Iwakura, Yoichiro, Aronow, Bruce J, Karns, Rebekah, Steinbrecher, Kris A, Karp, Christopher L, Sheridan, Rachel, Shanmukhappa, Shiva K, Reynaud, Damien, Haslam, David B, Sina, Christian, Rupp, Jan, Hogan, Simon P, Divanovic, Senad
Publicado no Nat Med (2017)