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Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen
BACKGROUND: Guanylate Cyclase C (GC-C) is an apically-oriented transmembrane receptor that is expressed on epithelial cells of the intestine. Activation of GC-C by the endogenous ligands guanylin or uroguanylin elevates intracellular cGMP and is implicated in intestinal ion secretion, cell prolifera...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3766218/ https://ncbi.nlm.nih.gov/pubmed/24004613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-13-135 |
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