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Murine Guanylate Cyclase C Regulates Colonic Injury and Inflammation
Guanylate cyclase C (GUCY2C or GC-C) and its ligands, guanylin (GUCA2A or Gn) and uroguanylin (GUCA2B or Ugn), are expressed in intestinal epithelial cells (IECs) and regulate ion secretion, intestinal barrier function, and epithelial monolayer homeostasis via cGMP-dependent signaling pathways. The...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110533/ https://ncbi.nlm.nih.gov/pubmed/21555532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002469 |
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