Á lódáil...
Guanylate Cyclase C Deficiency Causes Severe Inflammation in a Murine Model of Spontaneous Colitis
BACKGROUND: Guanylate Cyclase C (GC-C; Gucy2c) is a transmembrane receptor expressed in intestinal epithelial cells. Activation of GC-C by its secreted ligand guanylin stimulates intestinal fluid secretion. Familial mutations in GC-C cause chronic diarrheal disease or constipation and are associated...
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Main Authors: | , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Public Library of Science
2013
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823613/ https://ncbi.nlm.nih.gov/pubmed/24244444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079180 |
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