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Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice

In inflammatory bowel diseases (IBD), particularly ulcerative colitis (UC), intestinal macrophages (MΦs), eosinophils and the eosinophil-selective chemokine CCL11 have been associated with disease pathogenesis. MΦs, a source of CCL11, have been reported to be of a mixed classical (NF-κB-mediated) an...

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Bibliographic Details
Main Authors: Waddell, Amanda, Ahrens, Richard, Tsai, Yi Ting, Sherrill, Joseph D., Denson, Lee A., Steinbrecher, Kris A., Hogan, Simon P.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969817/
https://ncbi.nlm.nih.gov/pubmed/23562811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200057
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