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Thrombin drives tumorigenesis in colitis-associated colon cancer

The established association between inflammatory bowel disease and colorectal cancer underscores the importance of inflammation in colon cancer development. Based on evidence that hemostatic proteases are powerful modifiers of both inflammatory pathologies and tumor biology, gene-targeted mice carry...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Turpin, Brian, Miller, Whitney, Rosenfeldt, Leah, Kombrinck, Keith, Flick, Matthew J., Steinbrecher, Kris A., Harmel-Laws, Eleana, Mullins, Eric S., Shaw, Maureen, Witte, David P., Revenko, Alexey, Monia, Brett, Palumbo, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288815/
https://ncbi.nlm.nih.gov/pubmed/24710407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3276
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