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Deletion of Fanca or Fancd2 dysregulates Treg in mice

Fanconi anemia (FA) is a genetic disorder associated with bone marrow (BM) failure and leukemia. Recent studies demonstrate variable immune defects in FA. However, the cause for FA immunodeficiency is unknown. Here we report that deletion of Fanca or Fancd2 dysregulates the suppressive activity of r...

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Detalhes bibliográficos
Main Authors: Du, Wei, Erden, Ozlem, Wilson, Andrew, Sipple, Jared M., Schick, Jonathan, Mehta, Parinda, Myers, Kasiani C., Steinbrecher, Kris A., Davies, Stella M., Pang, Qishen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962166/
https://ncbi.nlm.nih.gov/pubmed/24501220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-528018
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