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Deletion of Fanca or Fancd2 dysregulates Treg in mice

Fanconi anemia (FA) is a genetic disorder associated with bone marrow (BM) failure and leukemia. Recent studies demonstrate variable immune defects in FA. However, the cause for FA immunodeficiency is unknown. Here we report that deletion of Fanca or Fancd2 dysregulates the suppressive activity of r...

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Bibliografiset tiedot
Päätekijät: Du, Wei, Erden, Ozlem, Wilson, Andrew, Sipple, Jared M., Schick, Jonathan, Mehta, Parinda, Myers, Kasiani C., Steinbrecher, Kris A., Davies, Stella M., Pang, Qishen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962166/
https://ncbi.nlm.nih.gov/pubmed/24501220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-528018
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