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Deletion of Fanca or Fancd2 dysregulates Treg in mice
Fanconi anemia (FA) is a genetic disorder associated with bone marrow (BM) failure and leukemia. Recent studies demonstrate variable immune defects in FA. However, the cause for FA immunodeficiency is unknown. Here we report that deletion of Fanca or Fancd2 dysregulates the suppressive activity of r...
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Päätekijät: | , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Society of Hematology
2014
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962166/ https://ncbi.nlm.nih.gov/pubmed/24501220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-528018 |
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