Deletion of Fanca or Fancd2 dysregulates Treg in mice

Fanconi anemia (FA) is a genetic disorder associated with bone marrow (BM) failure and leukemia. Recent studies demonstrate variable immune defects in FA. However, the cause for FA immunodeficiency is unknown. Here we report that deletion of Fanca or Fancd2 dysregulates the suppressive activity of r...

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Autors principals: Du, Wei, Erden, Ozlem, Wilson, Andrew, Sipple, Jared M., Schick, Jonathan, Mehta, Parinda, Myers, Kasiani C., Steinbrecher, Kris A., Davies, Stella M., Pang, Qishen
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Transplantation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962166/
https://ncbi.nlm.nih.gov/pubmed/24501220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-528018
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