Glycogen Synthase Kinase 3β Functions To Specify Gene-Specific, NF-κB-Dependent Transcription

Loss of glycogen synthase kinase 3β (GSK-3β) in mice results in embryonic lethality via hepatocyte apoptosis. Consistent with this result, cells from these mice have diminished nuclear factor κB (NF-κB) activity, implying a functional role for GSK-3β in regulating NF-κB. Here, we have explored mecha...

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Detalhes bibliográficos
Main Authors: Steinbrecher, Kris A., Wilson, Willie, Cogswell, Patricia C., Baldwin, Albert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265740/
https://ncbi.nlm.nih.gov/pubmed/16166627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8444-8455.2005
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