A20-binding Inhibitor of Nuclear Factor-κB (NF-κB)-2 (ABIN-2) Is an Activator of Inhibitor of NF-κB (IκB) Kinase α (IKKα)-mediated NF-κB Transcriptional Activity

NF-κB transcription factors are pivotal players in controlling inflammatory and immune responses, as well as cell proliferation and apoptosis. Aberrant regulation of NF-κB and the signaling pathways that regulate its activity have been involved in various pathologies, particularly cancers, as well a...

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Bibliographic Details
Main Authors: Leotoing, Laurent, Chereau, Fanny, Baron, Silvère, Hube, Florent, Valencia, Hugo J., Bordereaux, Didier, Demmers, Jeroen A., Strouboulis, John, Baud, Véronique
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173178/
https://ncbi.nlm.nih.gov/pubmed/21784860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236448
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