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NF-κB Activation during Rickettsia rickettsii Infection of Endothelial Cells Involves the Activation of Catalytic IκB Kinases IKKα and IKKβ and Phosphorylation-Proteolysis of the Inhibitor Protein IκBα

Rocky Mountain spotted fever, a systemic tick-borne illness caused by the obligate intracellular bacterium Rickettsia rickettsii, is associated with widespread infection of the vascular endothelium. R. rickettsii infection induces a biphasic pattern of the nuclear factor-κB (NF-κB) activation in cul...

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Bibliografske podrobnosti
Main Authors: Clifton, Dawn R., Rydkina, Elena, Freeman, Robert S., Sahni, Sanjeev K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC538953/
https://ncbi.nlm.nih.gov/pubmed/15618150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.155-165.2005
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