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Nuclear Factor κB Protects against Host Cell Apoptosis during Rickettsia rickettsii Infection by Inhibiting Activation of Apical and Effector Caspases and Maintaining Mitochondrial Integrity

Apoptotic host cell death is a critical determinant in the progression of microbial infections and outcome of resultant diseases. The potentially fatal human infection caused by Rickettsia rickettsii, the etiologic agent of Rocky Mountain spotted fever, involves the vascular endothelium of various o...

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Главные авторы: Joshi, Suresh G., Francis, Charles W., Silverman, David J., Sahni, Sanjeev K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC162038/
https://ncbi.nlm.nih.gov/pubmed/12819104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4127-4136.2003
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