Nuclear Factor κB Protects against Host Cell Apoptosis during Rickettsia rickettsii Infection by Inhibiting Activation of Apical and Effector Caspases and Maintaining Mitochondrial Integrity

Apoptotic host cell death is a critical determinant in the progression of microbial infections and outcome of resultant diseases. The potentially fatal human infection caused by Rickettsia rickettsii, the etiologic agent of Rocky Mountain spotted fever, involves the vascular endothelium of various o...

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Detalhes bibliográficos
Main Authors: Joshi, Suresh G., Francis, Charles W., Silverman, David J., Sahni, Sanjeev K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162038/
https://ncbi.nlm.nih.gov/pubmed/12819104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4127-4136.2003
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