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Attribution of NF-κB Activity to CHUK/IKKα-Involved Carcinogenesis

SIMPLE SUMMARY: CHUK/IKKα has emerged as a novel tumor suppressor in several organs of humans and mice. In general, activation of NF-κB promotes inflammation and tumorigenesis. IKKα reduction stimulates inflammatory responses including NF-κB’s targets and NF-κB-independent pathways for tumor promoti...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Li, Xin, Hu, Yinling
Format: Artigo
Language:Inglês
Published: MDPI 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003426/
https://ncbi.nlm.nih.gov/pubmed/33808757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061411
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