Human T-Cell Leukemia Virus Type 1 Tax Induction of NF-κB Involves Activation of the IκB Kinase α (IKKα) and IKKβ Cellular Kinases

Tax corresponds to a 40-kDa transforming protein from the pathogenic retrovirus human T-cell leukemia virus type 1 (HTLV-1) that activates nuclear expression of the NF-κB/Rel family of transcription factors by an unknown mechanism. Tax expression promotes N-terminal phosphorylation and degradation o...

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Main Authors: Geleziunas, Romas, Ferrell, Sharon, Lin, Xin, Mu, Yajun, Cunningham, Emmett T., Grant, Mark, Connelly, Margery A., Hambor, John E., Marcu, Kenneth B., Greene, Warner C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109101/
https://ncbi.nlm.nih.gov/pubmed/9710600
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