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Human T-Cell Leukemia Virus Type 1 Tax Induction of NF-κB Involves Activation of the IκB Kinase α (IKKα) and IKKβ Cellular Kinases

Tax corresponds to a 40-kDa transforming protein from the pathogenic retrovirus human T-cell leukemia virus type 1 (HTLV-1) that activates nuclear expression of the NF-κB/Rel family of transcription factors by an unknown mechanism. Tax expression promotes N-terminal phosphorylation and degradation o...

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Published in:Mol Cell Biol
Main Authors: Geleziunas, Romas, Ferrell, Sharon, Lin, Xin, Mu, Yajun, Cunningham, Emmett T., Grant, Mark, Connelly, Margery A., Hambor, John E., Marcu, Kenneth B., Greene, Warner C.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1998
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710600/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5157
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