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Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer’s disease
Two of the most predominant features of the Alzheimer’s disease (AD) brain are deposition of β-amyloid (Aβ) plaques and inflammation. The mechanism behind these pathologies remains unknown, but there is evidence to suggest that inflammation may predate the deposition of Aβ. Furthermore, immune activ...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187132/ https://ncbi.nlm.nih.gov/pubmed/30254165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811172115 |
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