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Direct Control of Cell Cycle Gene Expression by Proto-Oncogene Product ACTR, and Its Autoregulation Underlies Its Transforming Activity

ACTR (also called AIB1 and SRC-3) was identified as a coactivator for nuclear receptors and is linked to multiple types of human cancer due to its frequent overexpression. However, the molecular mechanism of ACTR oncogenicity and its function independent of nuclear receptors remain to be defined. We...

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Bibliografiske detaljer
Main Authors: Louie, Maggie C., Revenko, Alexey S., Zou, June X., Yao, Jennifer, Chen, Hong-Wu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489001/
https://ncbi.nlm.nih.gov/pubmed/16648476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.10.3810-3823.2006
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