ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2

Chromatin coregulators are important players in tumorigenesis and cancer progression. ANCCA is an AAA+ ATPase-containing nuclear coactivator for the estrogen and androgen receptors that is crucial for assembly of chromatin modifying complexes and proliferation of hormone-responsive cancer cells. In...

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Autori principali: Kalashnikova, Ekaterina V., Revenko, Alexey S., Gemo, Abigael T., Andrews, Nicolas P., Tepper, Clifford G., Zou, June X., Cardiff, Robert D., Borowsky, Alexander D., Chen, Hong-Wu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982862/
https://ncbi.nlm.nih.gov/pubmed/20864510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1199
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