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The ATAD2/ANCCA homolog Yta7 cooperates with Scm3(HJURP) to deposit Cse4(CENP-A) at the centromere in yeast

The AAA(+) ATPase and bromodomain factor ATAD2/ANCCA is overexpressed in many types of cancer, but how it contributes to tumorigenesis is not understood. Here, we report that the Saccharomyces cerevisiae homolog Yta7(ATAD2) is a deposition factor for the centromeric histone H3 variant Cse4(CENP-A) a...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Shahnejat-Bushehri, Sara, Ehrenhofer-Murray, Ann E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071854/
https://ncbi.nlm.nih.gov/pubmed/32079723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917814117
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