Activation of nuclear factor-κB is necessary for myotrophin-induced cardiac hypertrophy

Por Gupta, Sudhiranjan, Purcell, Nicole H., Lin, Anning, Sen, Subha
Publicado em 2002

Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

Por Purcell, Nicole H., Tang, Guilin, Yu, Chenfei, Mercurio, Frank, DiDonato, Joseph A., Lin, Anning
Publicado em 2001

PHLPP1 gene deletion protects the brain from ischemic injury

Por Chen, Bo, Van Winkle, Jessica A, Lyden, Patrick D, Brown, Joan H, Purcell, Nicole H
Publicado em 2013

Extracellular Signal-Regulated Kinase 2 Interacts with and Is Negatively Regulated by the LIM-Only Protein FHL2 in Cardiomyocytes

Por Purcell, Nicole H., Darwis, Dina, Bueno, Orlando F., Müller, Judith M., Schüle, Roland, Molkentin, Jeffery D.
Publicado em 2004

mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2

Por Kim, KyeongJin, Qiang, Li, Hayden, Matthew S., Sparling, David P., Purcell, Nicole H., Pajvani, Utpal B.
Publicado no Nat Commun (2016)

DUSP6 (MKP3) Null Mice Show Enhanced ERK1/2 Phosphorylation at Baseline and Increased Myocyte Proliferation in the Heart Affecting Disease Susceptibility

Por Maillet, Marjorie, Purcell, Nicole H., Sargent, Michelle A., York, Allen J., Bueno, Orlando F., Molkentin, Jeffery D.
Publicado em 2008

Sphingosine 1-Phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs

Por Castaldi, Alessandra, Chesini, Gino P., Taylor, Amy E., Sussman, Mark A., Brown, Joan Heller, Purcell, Nicole H.
Publicado no Cell Signal (2016)

Phospholipase Cɛ links G protein-coupled receptor activation to inflammatory astrocytic responses

Por Dusaban, Stephanie S., Purcell, Nicole H., Rockenstein, Edward, Masliah, Eliezer, Cho, Min Kyung, Smrcka, Alan V., Brown, Joan Heller
Publicado em 2013

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo

Por Purcell, Nicole H., Wilkins, Benjamin J., York, Allen, Saba-El-Leil, Marc K., Meloche, Sylvain, Robbins, Jeffrey, Molkentin, Jeffery D.
Publicado em 2007

Physiological activation of Akt by PHLPP1 deletion protects against pathological hypertrophy

Por Moc, Courtney, Taylor, Amy E., Chesini, Gino P., Zambrano, Cristina M., Barlow, Melissa S., Zhang, Xiaoxue, Gustafsson, Åsa B., Purcell, Nicole H.
Publicado no Cardiovasc Res (2015)

CaMKIIδ Mediates Myocardial Ischemia/Reperfusion Injury Through NF-κB

Por Ling, Haiyun, Gray, Charles B.B., Zambon, Alexander C., Grimm, Michael, Gu, Yusu, Dalton, Nancy, Purcell, Nicole H., Peterson, Kirk, Brown, Joan Heller
Publicado em 2013

PHLPP-1 Negatively Regulates Akt Activity and Survival in the Heart

Por Miyamoto, Shigeki, Purcell, Nicole H., Smith, Jeffrey M., Gao, Tianyan, Whittaker, Ross, Huang, Katherine, Castillo, Rene, Glembotski, Chris C., Sussman, Mark A., Newton, Alexandra C., Brown, Joan Heller
Publicado em 2010

Collagen XIV is important for growth and structural integrity of the myocardium

Por Tao, Ge, Levay, Agata K., Peacock, Jacqueline D., Huk, Danielle J., Both, Sarah N., Purcell, Nicole H., Pinto, Jose R., Galantowicz, Maarten L., Koch, Manuel, Lucchesi, Pamela A., Birk, David E., Lincoln, Joy
Publicado em 2012

RhoA protects the mouse heart against ischemia/reperfusion injury

Por Xiang, Sunny Yang, Vanhoutte, Davy, Del Re, Dominic P., Purcell, Nicole H., Ling, Haiyun, Banerjee, Indroneal, Bossuyt, Julie, Lang, Richard A., Zheng, Yi, Matkovich, Scot J., Miyamoto, Shigeki, Molkentin, Jeffery D., Dorn, Gerald W., Brown, Joan Heller
Publicado em 2011

APJ ACTS AS A DUAL RECEPTOR IN CARDIAC HYPERTROPHY

Por Scimia, Maria Cecilia, Hurtado, Cecilia, Ray, Saugata, Metzler, Scott, Wei, Ke, Wang, Jianming, Woods, Chris E., Purcell, Nicole H., Catalucci, Daniele, Akasaka, Takashi, Bueno, Orlando F., Vlasuk, George P., Kaliman, Perla, Bodmer, Rolf, Smith, Layton H., Ashley, Euan, Mercola, Mark, Brown, Joan Heller, Ruiz-Lozano, Pilar
Publicado em 2012