Redundancy in the World of MAP Kinases: All for One

od Saba-El-Leil, Marc K., Frémin, Christophe, Meloche, Sylvain
Wydane w Front Cell Dev Biol (2016)

Genetic Demonstration of a Redundant Role of Extracellular Signal-Regulated Kinase 1 (ERK1) and ERK2 Mitogen-Activated Protein Kinases in Promoting Fibroblast Proliferation

od Voisin, Laure, Saba-El-Leil, Marc K., Julien, Catherine, Frémin, Christophe, Meloche, Sylvain
Wydane 2010

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo

od Purcell, Nicole H., Wilkins, Benjamin J., York, Allen, Saba-El-Leil, Marc K., Meloche, Sylvain, Robbins, Jeffrey, Molkentin, Jeffery D.
Wydane 2007

Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models

od Soulez, Mathilde, Saba-El-Leil, Marc K., Turgeon, Benjamin, Mathien, Simon, Coulombe, Philippe, Klinger, Sonia, Rousseau, Justine, Lévesque, Kim, Meloche, Sylvain
Wydane w Mol Cell Biol (2019)

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

od Saba-El-Leil, Marc K., Vella, Francis D.J., Vernay, Bertrand, Voisin, Laure, Chen, Lan, Labrecque, Nathalie, Ang, Siew-Lan, Meloche, Sylvain
Wydane 2003

Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors

od Voisin, Laure, Julien, Catherine, Duhamel, Stéphanie, Gopalbhai, Kailesh, Claveau, Isabelle, Saba-El-Leil, Marc K, Rodrigue-Gervais, Ian Gaël, Gaboury, Louis, Lamarre, Daniel, Basik, Mark, Meloche, Sylvain
Wydane 2008

Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration

od Pyakurel, Aswin, Balmer, Delphine, Saba-El-Leil, Marc K., Kizilyaprak, Caroline, Daraspe, Jean, Humbel, Bruno M., Voisin, Laure, Le, Yun Z., von Lintig, Johannes, Meloche, Sylvain, Roduit, Raphaël
Wydane w Mol Cell Biol (2017)

ERK1/2 regulate the balance between eccentric and concentric cardiac growth

od Kehat, Izhak, Davis, Jennifer, Tiburcy, Malte, Accornero, Federica, Saba-El-Leil, Marc K., Maillet, Marjorie, York, Allen J., Lorenz, John N., Zimmermann, Wolfram H., Meloche, Sylvain, Molkentin, Jeffery D.
Wydane 2010

Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

od Wang, Jinyong, Kong, Guangyao, Liu, Yangang, Du, Juan, Chang, Yuan-I, Tey, Sin Ruow, Zhang, Xinmin, Ranheim, Erik A., Saba-El-Leil, Marc K., Meloche, Sylvain, Damnernsawad, Alisa, Zhang, Jingfang, Zhang, Jing
Wydane 2013

Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

od Deschênes-Simard, Xavier, Gaumont-Leclerc, Marie-France, Bourdeau, Véronique, Lessard, Frédéric, Moiseeva, Olga, Forest, Valérie, Igelmann, Sebastian, Mallette, Frédérick A., Saba-El-Leil, Marc K., Meloche, Sylvain, Saad, Fred, Mes-Masson, Anne-Marie, Ferbeyre, Gerardo
Wydane 2013

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

od Aubert, Léo, Nandagopal, Neethi, Steinhart, Zachary, Lavoie, Geneviève, Nourreddine, Sami, Berman, Jacob, Saba-El-Leil, Marc K., Papadopoli, David, Lin, Sichun, Hart, Traver, Macleod, Graham, Topisirovic, Ivan, Gaboury, Louis, Fahrni, Christoph J., Schramek, Daniel, Meloche, Sylvain, Angers, Stephane, Roux, Philippe P.
Wydane w Nat Commun (2020)