The mystery of oncogenic KRAS: Lessons from studying its wild-type counter part

Por Chang, Yuan-I, Damnernsawad, Alisa, Kong, Guangyao, You, Xiaona, Wang, Demin, Zhang, Jing
Publicado no Small GTPases (2016)

Embryonic Expression of Nras(G 12 D) Leads to Embryonic Lethality and Cardiac Defects

Por You, Xiaona, Ryu, Myung-Jeom, Cho, Eunjin, Sang, Yanzhi, Damnernsawad, Alisa, Zhou, Yun, Liu, Yangang, Zhang, Jing, Lee, Youngsook
Publicado no Front Cell Dev Biol (2021)

Kras is required for adult hematopoiesis

Por Damnernsawad, Alisa, Kong, Guangyao, Wen, Zhi, Liu, Yangang, Rajagopalan, Adhithi, You, Xiaona, Wang, Jinyong, Zhou, Yun, Ranheim, Erik A., Luo, Hongbo R., Chang, Qiang, Zhang, Jing
Publicado no Stem Cells (2016)

Proteolysis targeting chimeric molecules as therapy for multiple myeloma: efficacy, biomarker and drug combinations

Por Lim, Su Lin, Damnernsawad, Alisa, Shyamsunder, Pavithra, Chng, Wee Joo, Han, Bing Chen, Xu, Liang, Pan, Jian, Pravin, Dakle Pushkar, Alkan, Serhan, Tyner, Jeffrey W., Koeffler, H. Phillip
Publicado no Haematologica (2019)

Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis

Por Kong, Guangyao, Chang, Yuan-I, Damnernsawad, Alisa, You, Xiaona, Du, Juan, Ranheim, Erik A., Lee, Woojong, Ryu, Myung-Jeom, Zhou, Yun, Xing, Yongna, Chang, Qiang, Burd, Christin E., Zhang, Jing
Publicado no Leukemia (2016)

Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions

Por Wang, Jinyong, Kong, Guangyao, Liu, Yangang, Du, Juan, Chang, Yuan-I, Tey, Sin Ruow, Zhang, Xinmin, Ranheim, Erik A., Saba-El-Leil, Marc K., Meloche, Sylvain, Damnernsawad, Alisa, Zhang, Jingfang, Zhang, Jing
Publicado em 2013

The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption

Por Anderson, Sheila A., Nizzi, Christopher P., Chang, Yuan-I, Deck, Kathryn M., Schmidt, Paul J., Galy, Bruno, Damnernsawad, Alisa, Broman, Aimee T., Kendziorski, Christina, Hentze, Matthias W., Fleming, Mark D., Zhang, Jing, Eisenstein, Richard S.
Publicado em 2013

Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation

Por Chang, Yuan-I, Damnernsawad, Alisa, Allen, Laura K., Yang, David, Ranheim, Erik A., Young, Ken H., Zhang, Jingfang, Kong, Guangyao, Wang, Jinyong, Liu, Yangang, Fu, Hsu-Yuan, Yang, Chii-Shen, Guo, Junjie, Song, Hongjun, Zhang, Jing
Publicado em 2014

Kras-deficient T cells attenuate graft-versus-host disease but retain graft-versus-leukemia activity

Por Luo, Lan, Chen, Yuhong, Chen, Xiao, Zheng, Yongwei, Zhou, Vivian, Yu, Mei, Burns, Robert, Zhu, Wen, Fu, Guoping, Felix, Juan C., Hartley, Christopher, Damnernsawad, Alisa, Zhang, Jing, Wen, Renren, Drobyski, Williams R., Gao, Chunji, Wang, Demin
Publicado no J Immunol (2020)

Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm

Por Kong, Guangyao, Wunderlich, Mark, Yang, David, Ranheim, Erik A., Young, Ken H., Wang, Jinyong, Chang, Yuan-I, Du, Juan, Liu, Yangang, Tey, Sin Ruow, Zhang, Xinmin, Juckett, Mark, Mattison, Ryan, Damnernsawad, Alisa, Zhang, Jingfang, Mulloy, James C., Zhang, Jing
Publicado em 2014

CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

Por Edwards, David K., Watanabe-Smith, Kevin, Rofelty, Angela, Damnernsawad, Alisa, Laderas, Ted, Lamble, Adam, Lind, Evan F., Kaempf, Andy, Mori, Motomi, Rosenberg, Mara, d’Almeida, Amanda, Long, Nicola, Agarwal, Anupriya, Sweeney, David Tyler, Loriaux, Marc, McWeeney, Shannon K., Tyner, Jeffrey W.
Publicado no Blood (2019)