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Kras is required for adult hematopoiesis
Previous studies indicate that Kras is dispensable for fetal liver hematopoiesis, but its rolein adult hematopoiesis remains unclear. Here, we generated a Kras conditional knockout allele to address this question. Deletion of Kras in adult bone marrow is mediated by Vav-Cre or inducible Mx1-Cre. We...
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| 出版年: | Stem Cells |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358545/ https://ncbi.nlm.nih.gov/pubmed/26972179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2355 |
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