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The mystery of oncogenic KRAS: Lessons from studying its wild-type counter part
Using conditional knock-in mouse models, we and others have shown that despite the very high sequence identity between Nras and Kras proteins, oncogenic Kras displays a much stronger leukemogenic activity than oncogenic Nras in vivo. In this manuscript, we will summarize our recent work of character...
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| Publicado no: | Small GTPases |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680677/ https://ncbi.nlm.nih.gov/pubmed/27449543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1215656 |
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