Regulation of Iron Metabolism by Hepcidin under Conditions of Inflammation

od Schmidt, Paul J.
Izdano u J Biol Chem (2015)

Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2

od Schmidt, Paul J., Fleming, Mark D.
Izdano 2012

Modulation of hepcidin as therapy for primary and secondary iron overload disorders: pre-clinical models and approaches

od Schmidt, Paul J., Fleming, Mark D.
Izdano 2014

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

od Schmidt, Paul J., Andrews, Nancy C., Fleming, Mark D.
Izdano 2010

Murine mutants in the study of systemic iron metabolism and its disorders: an update on recent advances

od Bartnikas, Thomas B., Fleming, Mark D., Schmidt, Paul J.
Izdano 2012

Effects of Testosterone on Erythropoiesis in a Female Mouse Model of Anemia of Inflammation

od Guo, Wen, Schmidt, Paul J., Fleming, Mark D., Bhasin, Shalender
Izdano u Endocrinology (2016)

Transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

od Schmidt, Paul J., Toran, Paul T., Giannetti, Anthony M., Bjorkman, Pamela J., Andrews, Nancy C.
Izdano 2008

Combination therapy with a Tmprss6 RNAi-therapeutic and the oral iron chelator deferiprone additively diminishes secondary iron overload in a mouse model of β-thalassemia intermedi...

od Schmidt, Paul J, Racie, Tim, Westerman, Mark, Fitzgerald, Kevin, Butler, James S, Fleming, Mark D
Izdano u Am J Hematol (2015)

SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1

od Jeong, Seung Min, Lee, Jaewon, Schmidt, Paul J., Fleming, Mark D., Haigis, Marcia C.
Izdano u Oncogene (2014)

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(−/−) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia

od Schmidt, Paul J., Toudjarska, Iva, Sendamarai, Anoop K., Racie, Tim, Milstein, Stuart, Bettencourt, Brian R., Hettinger, Julia, Bumcrot, David, Fleming, Mark D.
Izdano 2013

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice

od Corradini, Elena, Schmidt, Paul J., Meynard, Delphine, Garuti, Cinzia, Montosi, Giuliana, Chen, Shanzhuo, Vukicevic, Slobodan, Pietrangelo, Antonello, Lin, Herbert Y., Babitt, Jodie L.
Izdano 2010

HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression

od Wu, Xing-gang, Wang, Yang, Wu, Qian, Cheng, Wai-Hang, Liu, Wenjing, Zhao, Yueshui, Mayeur, Claire, Schmidt, Paul J., Yu, Paul B., Wang, Fudi, Xia, Yin
Izdano u Blood (2014)

A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeos...

od Gutschow, Patrick, Schmidt, Paul J., Han, Huiling, Ostland, Vaughn, Bartnikas, Thomas B., Pettiglio, Michael A., Herrera, Carolina, Butler, James S., Nemeth, Elizabeta, Ganz, Tomas, Fleming, Mark D., Westerman, Mark
Izdano u Haematologica (2015)

Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses

od Radoshitzky, Sheli R., Abraham, Jonathan, Spiropoulou, Christina F., Kuhn, Jens H., Nguyen, Dan, Li, Wenhui, Nagel, Jane, Schmidt, Paul J., Nunberg, Jack H., Andrews, Nancy C., Farzan, Michael, Choe, Hyeryun
Izdano 2007

HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis

od White, Carine, Yuan, Xiaojing, Schmidt, Paul J., Bresciani, Erica, Samuel, Tamika K., Campagna, Dean, Hall, Caitlin, Bishop, Kevin, Calicchio, Monica L., Lapierre, Ariane, Ward, Diane M., Liu, Paul, Fleming, Mark D., Hamza, Iqbal
Izdano 2013

The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption

od Anderson, Sheila A., Nizzi, Christopher P., Chang, Yuan-I, Deck, Kathryn M., Schmidt, Paul J., Galy, Bruno, Damnernsawad, Alisa, Broman, Aimee T., Kendziorski, Christina, Hentze, Matthias W., Fleming, Mark D., Zhang, Jing, Eisenstein, Richard S.
Izdano 2013

NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms

od Santana-Codina, Naiara, Gableske, Sebastian, del Rey, Maria Quiles, Małachowska, Beata, Jedrychowski, Mark P., Biancur, Douglas E., Schmidt, Paul J., Fleming, Mark D., Fendler, Wojciech, Harper, J. Wade, Kimmelman, Alec C., Mancias, Joseph D.
Izdano u Haematologica (2019)

Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia

od Crispin, Andrew, Guo, Chaoshe, Chen, Caiyong, Campagna, Dean R., Schmidt, Paul J., Lichtenstein, Daniel, Cao, Chang, Sendamarai, Anoop K., Hildick-Smith, Gordon J., Huston, Nicholas C., Boudreaux, Jeanne, Bottomley, Sylvia S., Heeney, Matthew M., Paw, Barry H., Fleming, Mark D., Ducamp, Sarah
Izdano u J Clin Invest (2020)

Pseudouridine synthase 1 deficient mice, a model for Mitochondrial Myopathy with Sideroblastic Anemia, exhibit muscle morphology and physiology alterations

od Mangum, Joshua E., Hardee, Justin P., Fix, Dennis K., Puppa, Melissa J., Elkes, Johnathon, Altomare, Diego, Bykhovskaya, Yelena, Campagna, Dean R., Schmidt, Paul J., Sendamarai, Anoop K., Lidov, Hart G. W., Barlow, Shayne C., Fischel-Ghodsian, Nathan, Fleming, Mark D., Carson, James A., Patton, Jeffrey R.
Izdano u Sci Rep (2016)

UBE2O remodels the proteome during terminal erythroid differentiation

od Nguyen, Anthony T., Prado, Miguel A., Schmidt, Paul J., Sendamarai, Anoop T., Wilson-Grady, Joshua T., Min, Mingwei, Campagna, Dean R., Tian, Geng, Shi, Yuan, Dederer, Verena, Kawan, Mona, Kuehnle, Nathalie, Paulo, Joao A., Yao, Yu, Weiss, Mitchell J., Justice, Monica J., Gygi, Steven P., Fleming, Mark D., Finley, Daniel
Izdano u Science (2017)