A carregar...
Combination therapy with a Tmprss6 RNAi-therapeutic and the oral iron chelator deferiprone additively diminishes secondary iron overload in a mouse model of β-thalassemia intermedia
β-thalassemias result from diminished β-globin synthesis and are associated with ineffective erythropoiesis and secondary iron overload caused by inappropriately low levels of the iron regulatory hormone hepcidin. The serine protease TMPRSS6 attenuates hepcidin production in response to iron stores....
Na minha lista:
| Publicado no: | Am J Hematol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403964/ https://ncbi.nlm.nih.gov/pubmed/25557851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23934 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|