HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis

Adult humans have about 25 trillion red blood cells (RBCs) and each second we recycle about five million RBCs by erythrophagocytosis (EP) in macrophages of the reticuloendothelial system. Despite the central role for EP in mammalian iron metabolism, the molecules and pathways responsible for heme tr...

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Main Authors: White, Carine, Yuan, Xiaojing, Schmidt, Paul J., Bresciani, Erica, Samuel, Tamika K., Campagna, Dean, Hall, Caitlin, Bishop, Kevin, Calicchio, Monica L., Lapierre, Ariane, Ward, Diane M., Liu, Paul, Fleming, Mark D., Hamza, Iqbal
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582031/
https://ncbi.nlm.nih.gov/pubmed/23395172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.01.005
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