Hrg1 promotes heme-iron recycling during hemolysis in the zebrafish kidney

Heme-iron recycling from senescent red blood cells (erythrophagocytosis) accounts for the majority of total body iron in humans. Studies in cultured cells have ascribed a role for HRG1/SLC48A1 in heme-iron transport but the in vivo function of this heme transporter is unclear. Here we present geneti...

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Udgivet i:PLoS Genet
Main Authors: Zhang, Jianbing, Chambers, Ian, Yun, Sijung, Phillips, John, Krause, Michael, Hamza, Iqbal
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171960/
https://ncbi.nlm.nih.gov/pubmed/30248094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007665
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