Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Despite its importance in human cancers, including colorectal cancers (CRC), oncogenic KRAS has been extremely challenging to target therapeutically. To identify potential vulnerabilities in KRAS-mutated CRC, we characterize the impact of oncogenic KRAS on the cell surface of intestinal epithelial c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Aubert, Léo, Nandagopal, Neethi, Steinhart, Zachary, Lavoie, Geneviève, Nourreddine, Sami, Berman, Jacob, Saba-El-Leil, Marc K., Papadopoli, David, Lin, Sichun, Hart, Traver, Macleod, Graham, Topisirovic, Ivan, Gaboury, Louis, Fahrni, Christoph J., Schramek, Daniel, Meloche, Sylvain, Angers, Stephane, Roux, Philippe P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7381612/
https://ncbi.nlm.nih.gov/pubmed/32709883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17549-y
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