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Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo

MAPK signaling pathways function as critical regulators of cellular differentiation, proliferation, stress responsiveness, and apoptosis. One branch of the MAPK signaling pathway that culminates in ERK1/2 activation is hypothesized to regulate the growth and adaptation of the heart to both physiolog...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Purcell, Nicole H., Wilkins, Benjamin J., York, Allen, Saba-El-Leil, Marc K., Meloche, Sylvain, Robbins, Jeffrey, Molkentin, Jeffery D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955824/
https://ncbi.nlm.nih.gov/pubmed/17709754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610906104
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