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Genetic Demonstration of a Redundant Role of Extracellular Signal-Regulated Kinase 1 (ERK1) and ERK2 Mitogen-Activated Protein Kinases in Promoting Fibroblast Proliferation

The extracellular signal-regulated kinase 1 and 2 (ERK1/2) mitogen-activated protein (MAP) kinase signaling pathway plays an important role in the proliferative response of mammalian cells to mitogens. However, the individual contribution of the isoforms ERK1 and ERK2 to cell proliferation control i...

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Detalhes bibliográficos
Main Authors: Voisin, Laure, Saba-El-Leil, Marc K., Julien, Catherine, Frémin, Christophe, Meloche, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876689/
https://ncbi.nlm.nih.gov/pubmed/20368360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00131-10
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