Sphingosine 1-Phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs

Although c-kit(+) cardiac progenitor cells (CPCs) are currently used in clinical trials there remain considerable gaps in our understanding of the molecular mechanisms underlying their proliferation and differentiation. G-protein coupled receptors (GPCRs) play an important role in regulating these p...

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Bibliografske podrobnosti
izdano v:Cell Signal
Main Authors: Castaldi, Alessandra, Chesini, Gino P., Taylor, Amy E., Sussman, Mark A., Brown, Joan Heller, Purcell, Nicole H.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004781/
https://ncbi.nlm.nih.gov/pubmed/27094722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.04.006
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