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Nuclear RhoA signaling regulates MRTF-dependent SMC-specific transcription

We have previously shown that RhoA-mediated actin polymerization stimulates smooth muscle cell (SMC)-specific transcription by regulating the nuclear localization of the myocardin-related transcription factors (MRTFs). On the basis of the recent demonstration that nuclear G-actin regulates MRTF nucl...

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Detalhes bibliográficos
Main Authors: Staus, Dean P., Weise-Cross, Laura, Mangum, Kevin D., Medlin, Matt D., Mangiante, Lee, Taylor, Joan M., Mack, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121646/
https://ncbi.nlm.nih.gov/pubmed/24906914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01002.2013
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