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S1P Receptor 2 Signals Through the RGS-RhoGEF, LARG, To Promote Smooth Muscle Cell Differentiation
OBJECTIVE: The goals of this study were to identify the signaling pathway by which S1P activates RhoA in SMC and to evaluate the contribution of this pathway to the regulation of SMC phenotype. METHODS AND RESULTS: Using a combination of receptor-specific agonists and antagonists we identified S1PR2...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930832/ https://ncbi.nlm.nih.gov/pubmed/20702813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.209395 |
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