Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission

Proper completion of mitosis requires the concerted effort of multiple RhoGEFs. Here we show that leukemia-associated RhoGEF (LARG), a RhoA-specific RGS-RhoGEF, is required for abscission, the final stage of cytokinesis, in which the intercellular membrane is cleaved between daughter cells. LARG col...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Martz, Matthew K., Grabocka, Elda, Beeharry, Neil, Yen, Timothy J., Wedegaertner, Philip B.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2013
Предметы:
Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771942/
https://ncbi.nlm.nih.gov/pubmed/23885121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-07-0533
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы