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Opposing Roles of p190RhoGAP and Ect2 RhoGEF in Regulating Cytokinesis

Evidence suggests that p190RhoGAP (p190), a GTPase activating protein (GAP) specific for Rho, plays a role in cytokinesis. First, ectopic expression of p190 induces a multinucleated cellular phenotype. Second, endogenous p190 localizes to the cleavage furrow of dividing cells. Lastly, its levels are...

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Hlavní autoři: Mikawa, Masahito, Su, Ling, Parsons, Sarah J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791401/
https://ncbi.nlm.nih.gov/pubmed/18642445
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