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p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells

Previous studies demonstrated that p190RhoGAP (p190) negatively affects cytokinesis in a Rho-GAP-dependent manner, suggesting that regulation of Rho may be a critical mechanism of p190 action during cytokinesis. P190 localizes to the cleavage furrow (CF) of dividing cells, and its levels decrease du...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Su, Ling, Pertz, Olivier, Mikawa, Masahito, Hahn, Klaus, Parsons, Sarah J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731427/
https://ncbi.nlm.nih.gov/pubmed/19254711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.02.014
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