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p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells

Previous studies demonstrated that p190RhoGAP (p190) negatively affects cytokinesis in a Rho-GAP-dependent manner, suggesting that regulation of Rho may be a critical mechanism of p190 action during cytokinesis. P190 localizes to the cleavage furrow (CF) of dividing cells, and its levels decrease du...

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Autores principales: Su, Ling, Pertz, Olivier, Mikawa, Masahito, Hahn, Klaus, Parsons, Sarah J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731427/
https://ncbi.nlm.nih.gov/pubmed/19254711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.02.014
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