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A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells

The cytokinetic furrow is organized by the RhoA GTPase, which recruits actin and myosin II to the furrow and drives contractility. Here, we show that the RhoA GTPase-activting protein (GAP) p190RhoGAP-A (also known as ARHGAP35) has a role in cytokinesis and is involved in regulating levels of RhoA-G...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Manukyan, Arkadi, Ludwig, Kirsten, Sanchez-Manchinelly, Sergio, Parsons, Sarah J., Stukenberg, P. Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282047/
https://ncbi.nlm.nih.gov/pubmed/25359885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.151647
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