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The Tumor Suppressor, p190RhoGAP, Differentially Initiates Apoptosis and Confers Docetaxel Sensitivity to Breast Cancer Cells

p190RhoGAP (p190) is a negative regulator of RhoGTPases and a putative tumor suppressor, whose mechanism of tumor suppression is poorly defined. Ectopic expression of p190 induces various morphological phenotypes, including multinucleation, dendrite-like formation, and chromatin condensation, sugges...

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Hlavní autoři: Ludwig, Kirsten, Parsons, Sarah J.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111004/
https://ncbi.nlm.nih.gov/pubmed/21779478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911402680
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