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A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells

The cytokinetic furrow is organized by the RhoA GTPase, which recruits actin and myosin II to the furrow and drives contractility. Here, we show that the RhoA GTPase-activting protein (GAP) p190RhoGAP-A (also known as ARHGAP35) has a role in cytokinesis and is involved in regulating levels of RhoA-G...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Manukyan, Arkadi, Ludwig, Kirsten, Sanchez-Manchinelly, Sergio, Parsons, Sarah J., Stukenberg, P. Todd
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282047/
https://ncbi.nlm.nih.gov/pubmed/25359885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.151647
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