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Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1

Rho GTPases are integral to the regulation of actin cytoskeleton-dependent processes, including mitosis. Rho and leukemia-associated Rho guanine-nucleotide exchange factor (LARG), also known as ARHGEF12, are involved in mitosis as well as diseases such as cancer and heart disease. Since LARG has a r...

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Опубликовано в: :Cell Signal
Главные авторы: Helms, Michelle C., Grabocka, Elda, Martz, Matthew K., Fischer, Christopher C., Suzuki, Nobuchika, Wedegaertner, Philip B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679667/
https://ncbi.nlm.nih.gov/pubmed/26483157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.10.004
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