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Functional consequences of Gα(13) mutations that disrupt interaction with p115RhoGEF
The G-protein α subunit, α(13), regulates cell growth and differentiation through the monomeric Rho GTPase. α(13) activates Rho through direct stimulation of the guanine nucleotide exchange factor p115RhoGEF, which contains a regulator of G-protein signaling homology domain (RH) in its N-terminus. T...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1351220/ https://ncbi.nlm.nih.gov/pubmed/15735747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1208414 |
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